Genetic structure and related subtypes

H5N1 is a subtype of the species Influenza A virus of the Influenzavirus A genus of the Orthomyxoviridae family. Like all other influenza A subtypes, the H5N1 subtype is an RNA virus. It has a segmented genome of eight negative sense, single-strands of RNA, abbreviated as PB2, PB1, PA, HA, NP, NA, M and NS. HA codes for hemagglutinin, an antigenic glycoprotein found on the surface of the

H5N1 Terminology

H5N1 isolates are identified like this actual HPAI A(H5N1) example, A/chicken/Nakorn-Patom/Thailand/CU-K2/04(H5N1): A stands for the species of influenza (A, B or C).chicken is the species the isolate was found inNakorn-Patom/Thailand is the place this specific virus was isolatedCU-K2 identifies it from other influenza viruses isolated at the same place04 represents the year 2004H5 stands for the

H5N1 Genetics

The first known strain of HPAI A(H5N1) (called A/chicken/Scotland/59) killed two flocks of chickens in Scotland in 1959; but that strain was very different from the current highly pathogenic strain of H5N1. The dominant strain of HPAI A(H5N1) in 2004 evolved from 1999 to 2002 creating the Z genotype.[11] It has also been called "Asian lineage HPAI A(H5N1)". Asian lineage HPAI A(H5N1) is divided

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Influenza A virus subtype H5N1

Influenza A virus subtype H5N1, also known as A(H5N1) or simply H5N1, is a subtype of the Influenza A virus which can cause illness in humans and many other animal species.[1] A bird-adapted strain of H5N1, called HPAI A(H5N1) for "highly pathogenic avian influenza virus of type A of subtype H5N1", is the causative agent of H5N1 flu, commonly known as "avian influenza" or "bird flu". It is
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